Products
P-glycoprotein (P-gp) modulator; inhibits P-gp-mediated multidrug-resistance (MDR).
Vitamin D3 analog.
Prohormone of calcitriol. Major circulating form of vitamin D.
Prodrug of vitamin D3.
Vitamin D2 analog, VDR agonist.
Vitamin D receptor (VDR) agonist
(+)-Bicuculline is an antagonist of the GABAA receptor.
Potent D3 dopamine receptor agonist (Ki = 2.3 nM).
A potent and specific Aurora kinase B inhibitor
CYC116 (CYC-116)is an oral small molecule Aurora kinase/VEGFR2 inhibitor with antineoplastic activity.
Potent inhibitor of aurora kinases with Ki values to be 0.6, 18 and 4.6 nM for auraro A, B and C isotypes respectively.
Potent, reversible AMP-activated protein kinase (AMPK) activator.
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