Product Information
C13240  A 769662
Synonyms:A 769662
CAS No.:844499-71-4
Molecular Formula:C20H12N2O3S
Molecular Weight:360.39
Solubility:Soluble in DMSO, slightly Soluble in ethanol
Appearance:Off-white powder
Purity:>99%
Pakage:500mg,1g,2g
Storage:Desiccate at -20°C
Chemical Name:6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
A 769662    Introduction:

 

Chemical name: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Biological Activity

Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo.



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