Product Information
C13245  Abiraterone Acetate (CB7630)
Synonyms:CB 7630, CB-7630
CAS No.:154229-18-2
Molecular Formula:C26H33NO2
Molecular Weight:391.55
Solubility:Soluble in Chloroform and Methanol
Appearance:Off-White Solid
Storage:at -20℃ 2 years
Abiraterone Acetate (CB7630)   Introduction:
Chemical Name: 17-(3-Pyridyl)-5,16-androstadien-3beta-acetate
Biological Activity:
Abiraterone acetate has been seen to be a novel steroidal inhibitor of CYP17A1(C17,20 lyase), a cytoochrome p450 complex, a rate-limiting enzyme in androgen biosynthesis resulting in inhibtion of testosterone production in both the adrenals and the testes. It has been observed to decrease the DHEA, androstenedione and testosterone. The compound has been shown to be approximately 21-24 times more potent than ketoconazole and liarozole  in CYP17A1 lyase inhibition.

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