Product Information
C14040  Pomalidomide(CC-4047)
Synonyms:CC-4047, Actimid
CAS No.:19171-19-8
Molecular Formula:C13H11N3O4
Molecular Weight:273.24
Appearance:White solid
Storage:at -20℃ 2 years
Pomalidomide(CC-4047)   Introduction:
Biological Activity:
Pomalidomide is tumor necrosis factor-α inhibitor and a new immunomodulator with an IC50 of 1 μM. It is a derivative of thalidomide and is 10,000 times more potent than thalidomide in terms of inhibition of tumor necrosis factor-α. Additionally, it helps to restrict tumors’ necessary blood vessel growth. Compared to thalidomide, pomalidomide has demonstrated enhanced immunological effects in lab testing, including an approximately 500-2,000 times greater potency at stimulating the proliferation of T-cells. Like thalidomide, pomalidomide appears to function through multiple pathways to inhibit myeloma cells’ growth and survival.

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