Product Information
C13332  Atazanavir sulfate
Synonyms:BMS-232632-05, CGP-73547, Reyataz, Zrivada
CAS No.:229975-97-7
Molecular Formula:C38H52N6O7.H2SO4
Molecular Weight:802.93
Solubility:Unknown
Appearance:White powder
Purity:>99%
Pakage:1g,2g,5g
Storage:at -20℃ 2 years
Atazanavir sulfate    Introduction:
Biological Activity:

Atazanavir sulfate(BMS-232632-05) is a sulfate salt form of atazanavir (BMS-232632) that is an highly potent HIV protease inhibitor with EC50 and EC90 of 2.6~5.3 nM and 9~15 nM in cell culture. Atazanavir (BMS-232632) is generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with an EC50 of approximately 47 nM. Furthermore, Atazanavir (BMS-232632) is highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different combinations.

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