Product Information
C13349  AZD1152-HQPA(Barasertib)
Synonyms:Barasertib, AZD1152
CAS No.:722544-51 6
Molecular Formula:C26H30FN7O3
Molecular Weight:507.56
Solubility:DMSO
Appearance:Crystalline solid
Purity:>99%
Pakage:100mg,200mg,500mg,1g,2g
Storage:at -20℃ 2 years
AZD1152-HQPA(Barasertib)   Introduction:
Chemical Name: 
2-(5-((7-3-(Ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide

Biological Activity:
A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A ( Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively). At concentrations as low as 0.01 µM, AZD 1152 produced a significant (p<0.05) decrease in the ability of NB4 cells to proliferate by 48 hours


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