Product Information
C10599  (+)-Bicuculline
CAS No.:485-49-4
Molecular Formula:C20H17NO6
Molecular Weight:367.36
Solubility:soluble in benzene,chloroform,ethyl acetate. Sparingly soluble in alcohol and ether
Appearance:Pale yellow crystalline powder
Storage:Store at -2
(+)-Bicuculline   Introduction:
Chemical Name:(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-Methyl-1,3-Dioxolo[4,5-G]Lisoquinolin-5-Yl]Furo[3,4-E]-1,3-Benzodioxol-8(6H)-One; (+)-Bicuculline; D-Bicuculline; Nsc 32192;
Biological Activity:
(+)-Bicuculline is an antagonist of the GABAA receptor. (+)-Bicuculline is the parent compound of the water soluble N-methyl derivatives (-)-Bicuculline methiodide  and (-)-Bicuculline methobromide. Antagonism of the GABAA receptor by (+)-Bicuculline blocks the neurotransmission inhibition function of the GABA system, utilized to induce an artificial epileptic state in laboratory studies

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