Product Information
C11845  Pristimerin
Synonyms:Celastrol methyl ester
CAS No.:1258-84-0
Molecular Formula:C30H40O4
Molecular Weight:464.64
Solubility:Soluble in chloroform, ethyl acetate, ethanol and methanol,Insoluble in water
Appearance:Orange Needle Crystal
Purity:>98%
Pakage:20mg,50mg,100mg,500mg,1g
Storage:Store at -20°C
Pristimerin   Introduction:
Chemical Name: (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid methyl ester
Biological Activity:
Triterpenoid. Antitumor agent. Induces caspase-dependent apoptosis by inhibiting the chymotrypsin-like activity of the proteasome. Inhibits NF-κB activation via inhibition of IKKα or IKKβ. Inhibits induction of inducible nitric oxide synthase (iNOS; NOS II). Shows in vitro antimalarial and insecticidal activity. Induces mitochondrial cell death. Has antiproliferative, antifungal and antiviral properties. Potent and reversible monoacylglycerol lipase (MGL) inhibitor.

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